In one of the first behavioral studies on baeocystin—a psilocybin analog found in Psilocybe mushrooms—researchers found little to no psychedelic effect in rats. The compound showed poor brain penetration, with minimal impact on movement, anxiety, or sensory processing. While its metabolite norpsilocin reached the brain, levels were too low to produce noticeable changes, suggesting baeocystin alone may not drive the effects seen in whole-mushroom experiences.