Gut & Digestion

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Study

Brown Swordbelt Mushroom Heals Colitis in Mice

Brown Swordbelt Mushroom Heals Colitis in Mice

Brown swordbelt mushroom

What they found

Brown swordbelt polysaccharides lowered colon inflammation and restored gut barrier and bacteria balance in mice.

Brown swordbelt polysaccharides lowered colon inflammation and restored gut barrier and bacteria balance in mice.

How solid is it?

Animal

Animal

Animal

Animal

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Lyophyllum decastes

Lyophyllum decastes

Compound

polysaccharides

polysaccharides

Published in

Frontiers in Pharmacology

Frontiers in Pharmacology

Covered in Shroom Scan

Section

HEALTH & WELLNESS

HEALTH & WELLNESS

As it ran in Shroom Scan

Gut Repair Boost

Gut Repair Boost

Polysaccharides from the brown swordbelt mushroom (Lyophyllum decastes) reduced colon inflammation and healed intestinal damage in mice with colitis. The treatment lowered inflammatory markers (TNF-α, IL-6, IL-1β), boosted gut barrier proteins like ZO-1 and occludin, and restored microbial balance by increasing Lactobacillus and reducing Helicobacter.

Polysaccharides from the brown swordbelt mushroom (Lyophyllum decastes) reduced colon inflammation and healed intestinal damage in mice with colitis. The treatment lowered inflammatory markers (TNF-α, IL-6, IL-1β), boosted gut barrier proteins like ZO-1 and occludin, and restored microbial balance by increasing Lactobacillus and reducing Helicobacter.

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