Daldinia eschscholtzii, a marine fungus isolated from coral reefs, was shown to inhibit acetylcholinesterase (AChE), an enzyme targeted in Alzheimer’s treatment. The extract, which performed nearly as well as the drug Galantamine, contains compounds like 4,7-dihydroxycoumarin and interacted with the AChE enzyme, suggesting a new source of natural compounds for developing treatments.