Mood & Mental Health

·

Study

First Psilocybin Dose Made Brain Regions Communicate More Freely

First Psilocybin Dose Made Brain Regions Communicate More Freely

Psilocybin mushrooms

What they found

28 first-time users given 25 mg psilocybin gained 4.7 points in well-being after a month, linked to freer brain communication.

28 first-time users given 25 mg psilocybin gained 4.7 points in well-being after a month, linked to freer brain communication.

The number

4.7-point increase in well-being

How solid is it?

Early human

Early human

Human – pilot trial

Human – pilot trial

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin

psilocybin

Sample size

28 first-time psilocybin users

28 first-time psilocybin users

Published in

bioRxiv

bioRxiv

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

Brain Flexibility Boost

Brain Flexibility Boost

In a groundbreaking study, 28 first-time psilocybin users received a high dose (25 mg), resulting in a 4.7-point increase in well-being after a month. The study found that psilocybin made different parts of the brain communicate more freely, and this increased brain activity right after the dose was linked to lasting mental health benefits. It suggests that psilocybin might help "reorganize" the brain in a way that supports better mental well-being.

In a groundbreaking study, 28 first-time psilocybin users received a high dose (25 mg), resulting in a 4.7-point increase in well-being after a month. The study found that psilocybin made different parts of the brain communicate more freely, and this increased brain activity right after the dose was linked to lasting mental health benefits. It suggests that psilocybin might help "reorganize" the brain in a way that supports better mental well-being.

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