Safety & Toxicity

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Study

Heating Cordyceps Extract Removes Toxic Effects in Cells

Heating Cordyceps Extract Removes Toxic Effects in Cells

Cordyceps

What they found

Cold-water cordyceps extracts were toxic to mouse spleen cells, but heating above 158°F eliminated the toxicity.

Cold-water cordyceps extracts were toxic to mouse spleen cells, but heating above 158°F eliminated the toxicity.

The number

above 158°F

How solid is it?

Lab dish

Lab dish

In vitro (lab dish)

In vitro (lab dish)

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Cordyceps militaris

Cordyceps militaris

Published in

International Journal of Medicinal Mushrooms

International Journal of Medicinal Mushrooms

Covered in Shroom Scan

Section

GROWING & GOURMET

GROWING & GOURMET

As it ran in Shroom Scan

Heat-Safe Cordyceps

Heat-Safe Cordyceps

Cold-water extracts of Cordyceps militaris showed dose-dependent cytotoxicity in mouse spleen cells, but heating the extract above 158°F completely eliminated the toxic effects. Unlike previous hot-water studies, this cold extract’s cytotoxicity did not rely on the usual immune receptor (dectin-1), suggesting the presence of heat-sensitive harmful compounds.

Cold-water extracts of Cordyceps militaris showed dose-dependent cytotoxicity in mouse spleen cells, but heating the extract above 158°F completely eliminated the toxic effects. Unlike previous hot-water studies, this cold extract’s cytotoxicity did not rely on the usual immune receptor (dectin-1), suggesting the presence of heat-sensitive harmful compounds.

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