Mood & Mental Health

·

Study

Higher Psilocybin Doses Boost Self-Compassion, Driving Mental Health Gains

Higher Psilocybin Doses Boost Self-Compassion, Driving Mental Health Gains

Psilocybin mushrooms

What they found

A 25 mg psilocybin dose produced stronger self-compassion than 1 mg, and self-compassion predicted drops in depression and anxiety.

A 25 mg psilocybin dose produced stronger self-compassion than 1 mg, and self-compassion predicted drops in depression and anxiety.

The number

25 mg vs. 1 mg

How solid is it?

Early human

Early human

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin

psilocybin

Published in

Research Square

Research Square

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

Self-Compassion Boost

Self-Compassion Boost

Two studies—one observational and one clinical trial—found that higher doses of psilocybin (25 mg vs. 1 mg) led to significantly stronger positive emotional experiences, especially self-compassion. Self-compassion was the only factor that consistently predicted and mediated improvements in depression, anxiety, suicidal ideation, and overall well-being, even beyond mystical experiences or positive mood.

Two studies—one observational and one clinical trial—found that higher doses of psilocybin (25 mg vs. 1 mg) led to significantly stronger positive emotional experiences, especially self-compassion. Self-compassion was the only factor that consistently predicted and mediated improvements in depression, anxiety, suicidal ideation, and overall well-being, even beyond mystical experiences or positive mood.

Veterans Heal, Rivers Recover, and Mushroom Blends May Be Better

Read the original study ↗

Get Shroom Scan

Next study

Psilocybin May Help Treat Anorexia and Bulimia ›

Shroom Scan · Every Friday

Get Studies Like This, Translated, Every Week

Ten new studies a week, each boiled down to what it found and why it matters to you. Free, and one click to leave.

See what's inside →