Brain & Cognition

·

Review

How Psilocybin Helps the Brain Form New Connections

How Psilocybin Helps the Brain Form New Connections

Psilocybin mushrooms

What they found

Psilocybin appears to promote synaptic plasticity via 5-HT2A activation, more BDNF and dendritic spine growth.

Psilocybin appears to promote synaptic plasticity via 5-HT2A activation, more BDNF and dendritic spine growth.

How solid is it?

Review

Review

Narrative review

Narrative review

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin

psilocybin

Published in

nhsjs.com

nhsjs.com

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

Brain Rewiring

Brain Rewiring

Psilocybin, the active compound in “magic mushrooms,” appears to promote synaptic plasticity—the brain’s ability to form and reorganize connections—through mechanisms involving serotonin 5-HT2A receptor activation, increased brain-derived neurotrophic factor (BDNF), and enhanced dendritic spine growth.

Psilocybin, the active compound in “magic mushrooms,” appears to promote synaptic plasticity—the brain’s ability to form and reorganize connections—through mechanisms involving serotonin 5-HT2A receptor activation, increased brain-derived neurotrophic factor (BDNF), and enhanced dendritic spine growth.

Psilocybin’s Brain Boost, Tumor Immunity, and Mycoremediation Wins

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