Pain & Headache

·

Review

Ketamine, Psilocybin and LSD for Chronic Pain

Ketamine, Psilocybin and LSD for Chronic Pain

Psilocybin mushrooms

What they found

A review finds ketamine, psilocybin and LSD show promise for chronic pain including cancer pain, migraines and cluster headaches.

A review finds ketamine, psilocybin and LSD show promise for chronic pain including cancer pain, migraines and cluster headaches.

How solid is it?

Review

Review

Narrative review

Narrative review

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

ketamine; psilocybin; LSD

ketamine; psilocybin; LSD

Published in

Current Pain and Headache Reports

Current Pain and Headache Reports

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

Psychedelics for Pain

Psychedelics for Pain

Ketamine, psilocybin, and LSD show promise as alternatives for chronic pain management, particularly in cancer, migraines, and cluster headaches. By modulating serotonin and glutamate pathways, these substances reduce pain perception, enhance neuroplasticity, and improve emotional resilience.

Ketamine, psilocybin, and LSD show promise as alternatives for chronic pain management, particularly in cancer, migraines, and cluster headaches. By modulating serotonin and glutamate pathways, these substances reduce pain perception, enhance neuroplasticity, and improve emotional resilience.

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