Cancer

·

Study

Lactarius hatsudake Polysaccharide Shrank Liver Tumors in Mice

Lactarius hatsudake Polysaccharide Shrank Liver Tumors in Mice

Hatsutake

What they found

High-dose LHP from Lactarius hatsudake reduced liver tumor volume by 73% in mice, comparable to cisplatin but without toxicity.

High-dose LHP from Lactarius hatsudake reduced liver tumor volume by 73% in mice, comparable to cisplatin but without toxicity.

The number

reduced tumor volume by 73%, comparable to cisplatin (75%)

How solid is it?

Animal

Animal

Animal

Animal

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Lactarius hatsudake

Lactarius hatsudake

Compound

LHP

LHP

Published in

talenta.usu.ac.id

talenta.usu.ac.id

Covered in Shroom Scan

Section

HEALTH & WELLNESS

HEALTH & WELLNESS

As it ran in Shroom Scan

Anti-Cancer Promise

Anti-Cancer Promise

Chinese researchers found a polysaccharide (LHP) from Lactarius hatsudake mushrooms that potently inhibits liver cancer. In mice, high-dose LHP (500 mg/kg) reduced tumor volume by 73%, comparable to cisplatin (75%) but without toxicity. In cell studies, LHP at 1.6 mg/mL decreased cancer cell survival to 61.94% and colony formation to 53.77%. It induced apoptosis (3.40% at 1.6 mg/mL) and reduced invasion ability by 54.78%.

Chinese researchers found a polysaccharide (LHP) from Lactarius hatsudake mushrooms that potently inhibits liver cancer. In mice, high-dose LHP (500 mg/kg) reduced tumor volume by 73%, comparable to cisplatin (75%) but without toxicity. In cell studies, LHP at 1.6 mg/mL decreased cancer cell survival to 61.94% and colony formation to 53.77%. It induced apoptosis (3.40% at 1.6 mg/mL) and reduced invasion ability by 54.78%.

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