Brain & Cognition

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Review

Lion's Mane and Reishi Show Promise for Slowing Alzheimer's

Lion's Mane and Reishi Show Promise for Slowing Alzheimer's

Lion's mane, Reishi

What they found

Animal studies show lion's mane and reishi reduce brain inflammation and improve memory; in humans lion's mane raised NGF and BDNF.

Animal studies show lion's mane and reishi reduce brain inflammation and improve memory; in humans lion's mane raised NGF and BDNF.

How solid is it?

Review

Review

Narrative review

Narrative review

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Hericium erinaceus, Ganoderma lucidum

Hericium erinaceus, Ganoderma lucidum

Compound

NGF; BDNF; amyloid-β

NGF; BDNF; amyloid-β

Published in

International Journal of Medicinal Mushrooms

International Journal of Medicinal Mushrooms

Covered in Shroom Scan

Section

HEALTH & WELLNESS

HEALTH & WELLNESS

As it ran in Shroom Scan

Alzheimer’s Slowdown

Alzheimer’s Slowdown

Lion’s mane (Hericium erinaceus) and reishi (Ganoderma lucidum) reduced brain inflammation and improved memory in animal studies, with reishi also lowering amyloid-β buildup. In humans, lion’s mane supplements increased nerve growth factors like NGF and BDNF, showing early potential for slowing cognitive decline.

Lion’s mane (Hericium erinaceus) and reishi (Ganoderma lucidum) reduced brain inflammation and improved memory in animal studies, with reishi also lowering amyloid-β buildup. In humans, lion’s mane supplements increased nerve growth factors like NGF and BDNF, showing early potential for slowing cognitive decline.

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