Lion’s mane whole-mushroom biomass (Hericium erinaceus, full mycelium and young fruiting body, not an extract) taken daily for 6–12 months in 147 children shifted brain activity from slow, immature delta–theta waves toward higher-functioning beta1 rhythms. On standardized testing, cognitive scores rose from 30% to 64%, speech from 19% to 29%, adaptive behavior from 22% to 34%, and social–emotional function from 24% to 36%.