Cancer

·

Study

Lion's Mane-Made Nanoparticles Attack Bacteria and Colon Cancer Cells

Lion's Mane-Made Nanoparticles Attack Bacteria and Colon Cancer Cells

Lion's mane

What they found

Silver-copper nanoparticles made with lion's mane extract were 3.9-fold more toxic to colon cancer cells than to normal cells in lab tests.

Silver-copper nanoparticles made with lion's mane extract were 3.9-fold more toxic to colon cancer cells than to normal cells in lab tests.

The number

3.9-fold greater toxicity toward colon cancer cells

How solid is it?

Lab dish

Lab dish

In vitro (lab dish)

In vitro (lab dish)

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Hericium erinaceus

Hericium erinaceus

Compound

silver-copper nanoparticles

silver-copper nanoparticles

Published in

Applied Biosciences

Applied Biosciences

Covered in Shroom Scan

Section

HEALTH & WELLNESS

HEALTH & WELLNESS

As it ran in Shroom Scan

Nanoparticles Fight Cancer

Nanoparticles Fight Cancer

Researchers used lion's mane mushroom extract (Hericium erinaceus) to synthesize tiny silver-copper nanoparticles (9.3 nm) that showed stronger antibacterial and anticancer activity than the extract alone. Against S. aureus bacteria, the nanoparticles created 14.89 mm inhibition zones, while demonstrating 3.9-fold greater toxicity toward colon cancer cells compared to normal fibroblasts, indicating selectivity for cancer cells. This green synthesis approach uses only mushroom extract with no toxic chemicals, positioning these nanoparticles as potential antimicrobial and anticancer agents for biomedical applications.

Researchers used lion's mane mushroom extract (Hericium erinaceus) to synthesize tiny silver-copper nanoparticles (9.3 nm) that showed stronger antibacterial and anticancer activity than the extract alone. Against S. aureus bacteria, the nanoparticles created 14.89 mm inhibition zones, while demonstrating 3.9-fold greater toxicity toward colon cancer cells compared to normal fibroblasts, indicating selectivity for cancer cells. This green synthesis approach uses only mushroom extract with no toxic chemicals, positioning these nanoparticles as potential antimicrobial and anticancer agents for biomedical applications.

Shroom Scan #120: Mushrooms just built a working computer

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