Mood & Mental Health

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Study

Low-Dose Psilocybin Boosts Brain Chemicals in Rats Without Hallucinations

Low-Dose Psilocybin Boosts Brain Chemicals in Rats Without Hallucinations

Psilocybin mushrooms

What they found

Low psilocybin doses raised dopamine, serotonin and GABA in rats and reduced anxiety without hallucinogenic effects.

Low psilocybin doses raised dopamine, serotonin and GABA in rats and reduced anxiety without hallucinogenic effects.

The number

0.1–0.6 mg/kg

How solid is it?

Animal

Animal

Animal

Animal

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin

psilocybin

Published in

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

Microdosing

Microdosing

Low doses of psilocybin (0.1–0.6 mg/kg) boosted key brain chemicals like dopamine, serotonin, and GABA in rats without triggering hallucinogenic effects. The compound reduced anxiety, modulated stress hormones, and caused no DNA damage.

Low doses of psilocybin (0.1–0.6 mg/kg) boosted key brain chemicals like dopamine, serotonin, and GABA in rats without triggering hallucinogenic effects. The compound reduced anxiety, modulated stress hormones, and caused no DNA damage.

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