Mood & Mental Health

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Study

Low-Dose Psilocybin Eased OCD in a Twin

Low-Dose Psilocybin Eased OCD in a Twin

Psilocybin mushrooms

What they found

A case study of identical twins found low-dose psilocybin reduced OCD symptoms in the affected twin.

A case study of identical twins found low-dose psilocybin reduced OCD symptoms in the affected twin.

How solid is it?

Early human

Early human

Human – case report

Human – case report

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin

psilocybin

Sample size

identical twins

identical twins

Published in

OSF Preprints

OSF Preprints

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

For OCD

For OCD

A case study on identical twins showed that low-dose psilocybin significantly reduced OCD symptoms and improved quality of life for the affected twin. While it didn’t restore cognitive flexibility—essential for adapting to new challenges—it helped the twin better manage obsessions and compulsions, particularly when combined with therapy.

A case study on identical twins showed that low-dose psilocybin significantly reduced OCD symptoms and improved quality of life for the affected twin. While it didn’t restore cognitive flexibility—essential for adapting to new challenges—it helped the twin better manage obsessions and compulsions, particularly when combined with therapy.

FDA on Amanita, Pregnancy Research, and Easy Mushrooms to Grow

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