A new study was published on the pain-relieving effects of LSD and psilocybin, highlighting their potential as treatments for chronic pain. Unlike opioids, which show decreased effectiveness over time, LSD and psilocybin's efficacy increases with repeated treatments. The study, published in the South African Medical Journal, explores the history and mechanisms of action of these substances, noting their ability to not just reduce pain but also manage the experience of pain more holistically. The article emphasizes the multidimensional nature of pain and how these psychedelic substances address psychological, social, and spiritual aspects of pain management.