Gut & Digestion

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Study

Maitake Eases Colitis in Vitamin D–deficient Mice

Maitake Eases Colitis in Vitamin D–deficient Mice

Maitake

What they found

Maitake raised vitamin D levels and reduced gut inflammation in vitamin D–deficient mice with colitis, similar to vitamin D2 supplements.

Maitake raised vitamin D levels and reduced gut inflammation in vitamin D–deficient mice with colitis, similar to vitamin D2 supplements.

How solid is it?

Animal

Animal

Animal

Animal

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Grifola frondosa

Grifola frondosa

Compound

vitamin D₂

vitamin D₂

Published in

Molecular Nutrition & Food Research

Molecular Nutrition & Food Research

Covered in Shroom Scan

Section

HEALTH & WELLNESS

HEALTH & WELLNESS

As it ran in Shroom Scan

Easing Colitis

Easing Colitis

Maitake (Grifola frondosa) helped reduce gut inflammation in vitamin D–deficient mice with severe colitis. It improved vitamin D status by boosting 25(OH)D₂ levels, normalized key immune and gut barrier gene expression, and reduced immune cell buildup in the colon, showing effects comparable to direct vitamin D₂ supplementation.

Maitake (Grifola frondosa) helped reduce gut inflammation in vitamin D–deficient mice with severe colitis. It improved vitamin D status by boosting 25(OH)D₂ levels, normalized key immune and gut barrier gene expression, and reduced immune cell buildup in the colon, showing effects comparable to direct vitamin D₂ supplementation.

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