A meta-analysis of 16 studies on psilocybin-assisted therapy for depression found large benefits in both short-term (d = 1.69) and long-term (d = 2.10) outcomes, but no clear link between the number of therapy hours (4.5–18 h) and treatment success. While all studies included some therapy, differences in methods and reporting make it hard to rule out its role, highlighting the need for more standardized, rigorous research on how therapy dose impacts psychedelic treatment results.