An enzyme called laccase, isolated from mossy maze mushroom (Cerrena unicolor), significantly slowed the growth of CT-26 colon cancer cells while having much milder effects on healthy cells. Across multiple tests, laccase reduced cancer cell viability and proliferation in a dose-dependent manner. The half-maximal inhibitory concentration (IC₅₀) for cancer cells was 3.85 µg/mL, compared to 5.86 µg/mL for normal fibroblasts. The findings suggest strong therapeutic potential, especially since the enzyme also inhibited cancer cell migration without harming normal cell behavior.