Gut & Digestion

·

Study

Mushroom Prebiotic Improved Symptoms in 80% of Crohn's Patients

Mushroom Prebiotic Improved Symptoms in 80% of Crohn's Patients

Turkey tail, Lion's mane, Sun mushroom

What they found

A three-mushroom prebiotic improved symptoms in 80% of Crohn's patients versus 16.7% on placebo.

A three-mushroom prebiotic improved symptoms in 80% of Crohn's patients versus 16.7% on placebo.

The number

80% of Crohn’s patients, compared to just 16.7% on placebo

How solid is it?

Early human

Early human

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Trametes versicolor, Hericium erinaceus, Agaricus blazei Murill

Trametes versicolor, Hericium erinaceus, Agaricus blazei Murill

Compound

Mycodigest

Mycodigest

Published in

Journal of Dietary Supplements

Journal of Dietary Supplements

Covered in Shroom Scan

Section

HEALTH & WELLNESS

HEALTH & WELLNESS

As it ran in Shroom Scan

Crohn’s Care Boost

Crohn’s Care Boost

A commercial prebiotic made from three mushroom extracts improved symptoms in 80% of Crohn’s patients, compared to just 16.7% on placebo. The supplement, Mycodigest, also increased gut levels of short-chain fatty acid–producing bacteria like Parabacteroides distasonis and Faecalimonas umbilicata, while inflammatory markers remained unchanged. The study was partially funded by Mycolivia, the Israeli company behind the product. While the mushrooms aren’t named in the paper, Mycodigest is listed elsewhere as containing turkey tail (Trametes versicolor), lion’s mane (Hericium erinaceus), and sun mushroom (Agaricus blazei Murill). While the supplement is listed on Hebrew-language health sites, international access seems limited.

A commercial prebiotic made from three mushroom extracts improved symptoms in 80% of Crohn’s patients, compared to just 16.7% on placebo. The supplement, Mycodigest, also increased gut levels of short-chain fatty acid–producing bacteria like Parabacteroides distasonis and Faecalimonas umbilicata, while inflammatory markers remained unchanged. The study was partially funded by Mycolivia, the Israeli company behind the product. While the mushrooms aren’t named in the paper, Mycodigest is listed elsewhere as containing turkey tail (Trametes versicolor), lion’s mane (Hericium erinaceus), and sun mushroom (Agaricus blazei Murill). While the supplement is listed on Hebrew-language health sites, international access seems limited.

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