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Study

New Fungal Compounds Fight Inflammation and Bone Loss

New Fungal Compounds Fight Inflammation and Bone Loss

Biscogniauxia

What they found

Seven new diterpenoids from Biscogniauxia fungus reduced inflammatory signals and blocked osteoclast formation.

Seven new diterpenoids from Biscogniauxia fungus reduced inflammatory signals and blocked osteoclast formation.

The number

seven new compounds

How solid is it?

Lab dish

Lab dish

In vitro (lab dish)

In vitro (lab dish)

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Biscogniauxia sp.

Biscogniauxia sp.

Compound

diterpenoids (biscognisecoisopimarate B)

diterpenoids (biscognisecoisopimarate B)

Published in

authorea.com

authorea.com

Covered in Shroom Scan

Section

HEALTH & WELLNESS

HEALTH & WELLNESS

As it ran in Shroom Scan

Bone & Inflammation Aid

Bone & Inflammation Aid

Researchers discovered seven new compounds, called diterpenoids, from the fungus Biscogniauxia sp. Several showed strong anti-inflammatory activity by reducing IL-6 and TNF-α, while others blocked bone loss by preventing osteoclast formation. One compound, biscognisecoisopimarate B, had the most powerful bone-protecting effect.

Researchers discovered seven new compounds, called diterpenoids, from the fungus Biscogniauxia sp. Several showed strong anti-inflammatory activity by reducing IL-6 and TNF-α, while others blocked bone loss by preventing osteoclast formation. One compound, biscognisecoisopimarate B, had the most powerful bone-protecting effect.

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