Mood & Mental Health

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Study

One or Two Psilocybin Doses Both Treat Major Depression

One or Two Psilocybin Doses Both Treat Major Depression

Psilocybin mushrooms

What they found

A study found both one and two psilocybin doses effectively treat major and treatment-resistant depression, without a clear winner.

A study found both one and two psilocybin doses effectively treat major and treatment-resistant depression, without a clear winner.

How solid is it?

Early human

Early human

Human – clinical study

Human – clinical study

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin

psilocybin

Published in

Shroomer

Shroomer

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

One or Two

One or Two

A new study found that both one and two doses of psilocybin effectively treat Major Depressive Disorder (MDD) and Treatment-Resistant Depression (TRD). Although the research shows a lot of benefits for both dosing strategies, it doesn't conclusively favor one over the other.

A new study found that both one and two doses of psilocybin effectively treat Major Depressive Disorder (MDD) and Treatment-Resistant Depression (TRD). Although the research shows a lot of benefits for both dosing strategies, it doesn't conclusively favor one over the other.

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