Brain & Cognition

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Study

One Psilocybin Dose Reshapes Rat Brain Rhythms for Days

One Psilocybin Dose Reshapes Rat Brain Rhythms for Days

Psilocybin mushrooms

What they found

A single psilocybin dose changed prefrontal cortex activity in rats, with brain wave changes lasting several days.

A single psilocybin dose changed prefrontal cortex activity in rats, with brain wave changes lasting several days.

How solid is it?

Animal

Animal

Animal

Animal

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin

psilocybin

Published in

Molecular Psychiatry

Molecular Psychiatry

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

Brain Activity Shifts

Brain Activity Shifts

In rats, a single psilocybin dose reshaped activity in the prefrontal cortex, a brain region tied to mood and decision-making. It triggered new high-frequency rhythms and reduced cell firing right away, while longer-lasting changes in brain wave patterns appeared over the next several days.

In rats, a single psilocybin dose reshaped activity in the prefrontal cortex, a brain region tied to mood and decision-making. It triggered new high-frequency rhythms and reduced cell firing right away, while longer-lasting changes in brain wave patterns appeared over the next several days.

Skin Glow, Psilocybin Access, and Fungi vs. Oil Spills

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