Safety & Toxicity

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Study

People With Personality Disorders More Likely to React Badly to Psychedelics

People With Personality Disorders More Likely to React Badly to Psychedelics

What they found

31% of people with personality disorders had negative reactions to psychedelics, versus mostly positive responses in depression and anxiety.

31% of people with personality disorders had negative reactions to psychedelics, versus mostly positive responses in depression and anxiety.

The number

31% of people with personality disorders had negative reactions

How solid is it?

Early human

Early human

Human – observational/survey

Human – observational/survey

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Published in

Shroomer

Shroomer

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

Risk Factors

Risk Factors

New research shows that 31% of people with personality disorders had negative reactions to psychedelics, compared to over two-thirds of positive responses in those with depression, anxiety, or eating disorders. “Understanding who may not respond well to psychedelics is crucial for improving treatment safety,” the study notes, emphasizing the need for personalized approaches.

New research shows that 31% of people with personality disorders had negative reactions to psychedelics, compared to over two-thirds of positive responses in those with depression, anxiety, or eating disorders. “Understanding who may not respond well to psychedelics is crucial for improving treatment safety,” the study notes, emphasizing the need for personalized approaches.

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