Pink oyster mushrooms (Pleurotus djamor) readily absorbed cadmium when grown on contaminated substrates, reaching levels far above the World Health Organization’s safe limit of 0.1 mg/kg. Even mushrooms grown on “clean” substrates contained measurable cadmium (1.8 mg/kg), and at the highest contamination level, mushrooms reached 23.8 mg/kg. Health risk analysis (THQ values) showed cadmium exposure from these mushrooms could exceed safe thresholds for both adults and children, highlighting serious food safety concerns and the need for strict monitoring.