Mood & Mental Health

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Study

Poor Sleep May Blunt Psilocybin’s Benefits for Depression

Poor Sleep May Blunt Psilocybin’s Benefits for Depression

Psilocybin mushrooms

What they found

In 653 retreat participants, psilocybin improved sleep and depression for up to 4 weeks, but poor baseline sleep predicted worse outcomes.

In 653 retreat participants, psilocybin improved sleep and depression for up to 4 weeks, but poor baseline sleep predicted worse outcomes.

The number

653 retreat participants

How solid is it?

Early human

Early human

Human – observational/survey

Human – observational/survey

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin

psilocybin

Sample size

653 retreat participants

653 retreat participants

Published in

Current Psychiatry Reports

Current Psychiatry Reports

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

Sleep Like a Baby

Sleep Like a Baby

A new Johns Hopkins study of 653 retreat participants finds that while psilocybin improved both sleep and depression symptoms for up to 4 weeks, poor sleep at baseline predicted worse therapeutic outcomes.

A new Johns Hopkins study of 653 retreat participants finds that while psilocybin improved both sleep and depression symptoms for up to 4 weeks, poor sleep at baseline predicted worse therapeutic outcomes.

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