Brain & Cognition

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Study

Psilocybe cubensis Extract Restored Memory in Stressed Rats

Psilocybe cubensis Extract Restored Memory in Stressed Rats

Psilocybin mushrooms

What they found

Psilocybe cubensis extract given 24–48 hours before training restored memory and raised BDNF in stressed rats.

Psilocybe cubensis extract given 24–48 hours before training restored memory and raised BDNF in stressed rats.

The number

24–48 hours before training

How solid is it?

Animal

Animal

Animal

Animal

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Psilocybe cubensis

Psilocybe cubensis

Compound

psilocybin

psilocybin

Published in

Journal of Psychoactive Drugs

Journal of Psychoactive Drugs

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

Remember When

Remember When

Psilocybe cubensis extract improved memory and brain health in stressed rats but had mixed effects depending on timing. Administered 24–48 hours before training, it restored memory and increased BDNF, a brain growth protein. However, other timings impaired memory in unstressed rats, highlighting the importance of dosing schedules for therapeutic use.

Psilocybe cubensis extract improved memory and brain health in stressed rats but had mixed effects depending on timing. Administered 24–48 hours before training, it restored memory and increased BDNF, a brain growth protein. However, other timings impaired memory in unstressed rats, highlighting the importance of dosing schedules for therapeutic use.

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