Brain & Cognition

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Study

Psilocybin Affects Rats Differently by Age and Sex

Psilocybin Affects Rats Differently by Age and Sex

Psilocybin mushrooms

What they found

Adult rats showed strong head-twitch responses to psilocybin while adolescents showed none; females reacted more in the follicular phase.

Adult rats showed strong head-twitch responses to psilocybin while adolescents showed none; females reacted more in the follicular phase.

How solid is it?

Animal

Animal

Animal

Animal

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin

psilocybin

Published in

bioRxiv

bioRxiv

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

Sensitivity Differences

Sensitivity Differences

Psilocybin affects rats differently by age and sex. Adults show strong head twitch responses, while adolescents show none, indicating developmental differences. Female rats react more during the follicular phase, suggesting hormonal influence on sensitivity.

Psilocybin affects rats differently by age and sex. Adults show strong head twitch responses, while adolescents show none, indicating developmental differences. Female rats react more during the follicular phase, suggesting hormonal influence on sensitivity.

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