Brain & Cognition

·

Study

Psilocybin and DMT Make It Easier for the Brain to Switch States

Psilocybin and DMT Make It Easier for the Brain to Switch States

Psilocybin mushrooms

What they found

Psilocybin and DMT lowered the brain's control energy by over 60%, easing switches between brain states.

Psilocybin and DMT lowered the brain's control energy by over 60%, easing switches between brain states.

The number

over 60%

How solid is it?

Unclear

Unclear

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin; DMT

psilocybin; DMT

Published in

Communications Biology

Communications Biology

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

Brain Shift Signal

Brain Shift Signal

Psilocybin and DMT lowered the brain’s control energy by over 60%, making it easier for the brain to switch between different states. This shift was strongest in regions rich in serotonin 2A receptors and linked to more vivid experiences and increased brain signal diversity.

Psilocybin and DMT lowered the brain’s control energy by over 60%, making it easier for the brain to switch between different states. This shift was strongest in regions rich in serotonin 2A receptors and linked to more vivid experiences and increased brain signal diversity.

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