Brain & Cognition

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Review

Psilocybin Boosts Glutamate to Enhance Brain Plasticity

Psilocybin Boosts Glutamate to Enhance Brain Plasticity

Psilocybin mushrooms

What they found

Psilocybin boosts glutamate in mood and cognition areas by activating serotonin receptors, enhancing neuroplasticity.

Psilocybin boosts glutamate in mood and cognition areas by activating serotonin receptors, enhancing neuroplasticity.

How solid is it?

Review

Review

Narrative review

Narrative review

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin

psilocybin

Published in

Pharmacological Reports

Pharmacological Reports

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

More Brain Connection

More Brain Connection

Psilocybin was found to interact with the brain's glutamate and GABA systems. By activating specific serotonin receptors, psilocybin boosts glutamate levels in areas tied to mood and cognitive function, helping enhance neuroplasticity. This effect supports mental health treatments, including those for depression and addiction.

Psilocybin was found to interact with the brain's glutamate and GABA systems. By activating specific serotonin receptors, psilocybin boosts glutamate levels in areas tied to mood and cognitive function, helping enhance neuroplasticity. This effect supports mental health treatments, including those for depression and addiction.

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