Brain & Cognition

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Study

Psilocybin Disrupts Navigation and Memory Signals in Mouse Brains

Psilocybin Disrupts Navigation and Memory Signals in Mouse Brains

Psilocybin mushrooms

What they found

Psilocybin disrupted spatial encoding in the mouse retrosplenial cortex, which may explain disorientation.

Psilocybin disrupted spatial encoding in the mouse retrosplenial cortex, which may explain disorientation.

How solid is it?

Animal

Animal

Animal

Animal

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin

psilocybin

Published in

European Journal of Neuroscience

European Journal of Neuroscience

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

Altered States Explored

Altered States Explored

A recent study explores how psilocybin impacts brain activity in mice. The research revealed that psilocybin disrupts the normal patterns of spatial encoding in the brain, particularly in the retrosplenial cortex, an area linked to navigation and memory. This disruption leads to decreased stability and connectivity among neurons, which may explain why people often feel disoriented or experience altered perceptions.

A recent study explores how psilocybin impacts brain activity in mice. The research revealed that psilocybin disrupts the normal patterns of spatial encoding in the brain, particularly in the retrosplenial cortex, an area linked to navigation and memory. This disruption leads to decreased stability and connectivity among neurons, which may explain why people often feel disoriented or experience altered perceptions.

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Review: Psilocybin Does Not Harm Overall Thinking Skills ›

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