Brain & Cognition

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Study

Psilocybin Improves Long-Term Learning Flexibility in Rats

Psilocybin Improves Long-Term Learning Flexibility in Rats

Psilocybin mushrooms

What they found

Psilocybin briefly impaired learning in rats but later improved cognitive flexibility.

Psilocybin briefly impaired learning in rats but later improved cognitive flexibility.

How solid is it?

Animal

Animal

Animal

Animal

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin

psilocybin

Published in

OSF Preprints

OSF Preprints

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

Cognitive Flexibility

Cognitive Flexibility

In a rat study, psilocybin temporarily impaired learning and decision-making but led to long-term improvements in cognitive flexibility. Using a touchscreen-based reversal learning task, researchers found that rats initially struggled to adapt to new information after psilocybin, but over time, their learning speed improved.

In a rat study, psilocybin temporarily impaired learning and decision-making but led to long-term improvements in cognitive flexibility. Using a touchscreen-based reversal learning task, researchers found that rats initially struggled to adapt to new information after psilocybin, but over time, their learning speed improved.

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