Mood & Mental Health

·

Review

Psilocybin Lowers Inflammation Markers and Raises BDNF

Psilocybin Lowers Inflammation Markers and Raises BDNF

Psilocybin mushrooms

What they found

A systematic review of nine studies with 241 healthy people found psilocybin lowered IL-6 and CRP and raised BDNF.

A systematic review of nine studies with 241 healthy people found psilocybin lowered IL-6 and CRP and raised BDNF.

The number

nine studies involving 241 healthy participants

How solid is it?

Strong human

Strong human

Meta-analysis/systematic review

Meta-analysis/systematic review

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin; IL-6; CRP; BDNF

psilocybin; IL-6; CRP; BDNF

Sample size

241 healthy participants

241 healthy participants

Published in

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

Pathways to Relief

Pathways to Relief

A systematic review of nine studies involving 241 healthy participants found psilocybin influences biomarkers linked to depression, including decreases in inflammatory markers like IL-6 and CRP, and increases in neuroplasticity-related BDNF and hormones like cortisol and oxytocin.

A systematic review of nine studies involving 241 healthy participants found psilocybin influences biomarkers linked to depression, including decreases in inflammatory markers like IL-6 and CRP, and increases in neuroplasticity-related BDNF and hormones like cortisol and oxytocin.

Psilocybin Breakthrough, Gut-Healing Chanterelles, and Mushrooms vs. Plastic

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