Mood & Mental Health

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Review

Psilocybin Most Effective Psychedelic for End-of-Life Distress

Psilocybin Most Effective Psychedelic for End-of-Life Distress

Psilocybin mushrooms

What they found

Psilocybin significantly reduced depression and anxiety in terminally ill patients with no major safety concerns.

Psilocybin significantly reduced depression and anxiety in terminally ill patients with no major safety concerns.

How solid is it?

Early human

Early human

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin

psilocybin

Published in

Journal of Psychopharmacology

Journal of Psychopharmacology

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

End-of-Life Anxiety

End-of-Life Anxiety

Psilocybin significantly reduced depression and anxiety in terminally ill patients, improving overall quality of life. This study showed it’s the most effective psychedelic for easing existential distress, with no major safety concerns, offering hope for compassionate end-of-life care.

Psilocybin significantly reduced depression and anxiety in terminally ill patients, improving overall quality of life. This study showed it’s the most effective psychedelic for easing existential distress, with no major safety concerns, offering hope for compassionate end-of-life care.

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