Mood & Mental Health

·

Review

Psilocybin Reduced OCD Behaviors Across 13 Studies

Psilocybin Reduced OCD Behaviors Across 13 Studies

Psilocybin mushrooms

What they found

Across 13 animal and human studies, psilocybin consistently reduced obsessive and compulsive behaviors.

Across 13 animal and human studies, psilocybin consistently reduced obsessive and compulsive behaviors.

The number

Across 13 animal and human studies

How solid is it?

Review

Review

Meta-analysis/systematic review

Meta-analysis/systematic review

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin

psilocybin

Sample size

13 studies

13 studies

Published in

genomicpress.kglmeridian.com

genomicpress.kglmeridian.com

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

OCD Overview

OCD Overview

Across 13 animal and human studies, psilocybin consistently reduced obsessive and compulsive behaviors by rebalancing serotonin signaling and restoring flexible brain network activity. Low to moderate doses improved cognitive control and reduced anxiety-driven repetition, mirroring antidepressant effects without long-term side effects.

Across 13 animal and human studies, psilocybin consistently reduced obsessive and compulsive behaviors by rebalancing serotonin signaling and restoring flexible brain network activity. Low to moderate doses improved cognitive control and reduced anxiety-driven repetition, mirroring antidepressant effects without long-term side effects.

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