Mood & Mental Health

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Study

Psilocybin Restores the Ability to Feel Pleasure

Psilocybin Restores the Ability to Feel Pleasure

Psilocybin mushrooms

What they found

Two psilocybin doses gave fast, lasting relief of anhedonia for up to three months.

Two psilocybin doses gave fast, lasting relief of anhedonia for up to three months.

The number

up to three months

How solid is it?

Early human

Early human

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin

psilocybin

Published in

PCN Reports : Psychiatry and Clinical Neurosciences

PCN Reports : Psychiatry and Clinical Neurosciences

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

Pleasure Restored

Pleasure Restored

In people who couldn’t feel joy, two doses of psilocybin led to fast, lasting improvements in mood and motivation. It worked where typical antidepressants often fall short, helping reset the brain’s reward system and easing anhedonia for up to three months.

In people who couldn’t feel joy, two doses of psilocybin led to fast, lasting improvements in mood and motivation. It worked where typical antidepressants often fall short, helping reset the brain’s reward system and easing anhedonia for up to three months.

Gut Health Boost, Diabetes Defense, and Psilocybin’s Joy Reset

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