Addiction

·

Study

Psilocybin Shows Most Promise Among Psychedelics for Quitting Smoking

Psilocybin Shows Most Promise Among Psychedelics for Quitting Smoking

Psilocybin mushrooms

What they found

Across eight studies, psilocybin showed the strongest potential of classic psychedelics to help people quit smoking.

Across eight studies, psilocybin showed the strongest potential of classic psychedelics to help people quit smoking.

The number

used in 7 of 8 trials

How solid is it?

Strong human

Strong human

Meta-analysis/systematic review

Meta-analysis/systematic review

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin

psilocybin

Sample size

eight studies

eight studies

Published in

Journal of Psychopharmacology

Journal of Psychopharmacology

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

Quit Support

Quit Support

Across eight studies, psilocybin showed the strongest potential among classic psychedelics for helping people quit or reduce smoking. It was the most studied compound (used in 7 of 8 trials), outperforming LSD, mescaline, and ayahuasca in frequency and reported outcomes. While all studies had a high risk of bias, results suggest psilocybin may help disrupt nicotine addiction.

Across eight studies, psilocybin showed the strongest potential among classic psychedelics for helping people quit or reduce smoking. It was the most studied compound (used in 7 of 8 trials), outperforming LSD, mescaline, and ayahuasca in frequency and reported outcomes. While all studies had a high risk of bias, results suggest psilocybin may help disrupt nicotine addiction.

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