Pain & Headache

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Study

Psychedelic Users Had 25% Lower Odds of Frequent Bad Headaches

Psychedelic Users Had 25% Lower Odds of Frequent Bad Headaches

Psilocybin mushrooms

What they found

In over 11,000 people, past psychedelic users had 25% lower odds of frequent bad headaches, 30% in women.

In over 11,000 people, past psychedelic users had 25% lower odds of frequent bad headaches, 30% in women.

The number

25% lower odds of frequent bad headaches

How solid is it?

Early human

Early human

Human – observational/survey

Human – observational/survey

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin; LSD

psilocybin; LSD

Sample size

11,000+ people

11,000+ people

Published in

Journal of Psychopharmacology

Journal of Psychopharmacology

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

Headache Risk

Headache Risk

A study of 11,000+ people found that those who had used classic psychedelics like LSD or psilocybin had 25% lower odds of frequent bad headaches. The effect was strongest in women, who had a 30% reduced risk. While this doesn’t prove psychedelics prevent headaches, it adds to growing evidence that they’re an option for migraine and cluster headache relief.

A study of 11,000+ people found that those who had used classic psychedelics like LSD or psilocybin had 25% lower odds of frequent bad headaches. The effect was strongest in women, who had a 30% reduced risk. While this doesn’t prove psychedelics prevent headaches, it adds to growing evidence that they’re an option for migraine and cluster headache relief.

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