Safety & Toxicity

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Review

Raw Shiitake Can Cause a Rare Whip-Like Rash

Raw Shiitake Can Cause a Rare Whip-Like Rash

Shiitake

What they found

Eating raw or undercooked shiitake can trigger a rare whip-like rash 24–72 hours later; about 150 cases are reported and cooking prevents it.

Eating raw or undercooked shiitake can trigger a rare whip-like rash 24–72 hours later; about 150 cases are reported and cooking prevents it.

The number

~150 cases reported worldwide

How solid is it?

Early human

Early human

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Lentinula edodes

Lentinula edodes

Compound

lentinan

lentinan

Published in

Diagnostics

Diagnostics

Covered in Shroom Scan

Section

HEALTH & WELLNESS

HEALTH & WELLNESS

As it ran in Shroom Scan

Shiitake Rash Reaction

Shiitake Rash Reaction

Eating raw or undercooked shiitake mushrooms (Lentinula edodes) can trigger a distinctive whip-like skin rash that appears 24–72 hours after eating in sensitive people. The reaction is linked to lentinan, a mushroom polysaccharide that can trigger a hypersensitivity response and produce linear red lesions across the trunk and arms. The condition is rare with ~150 cases reported worldwide and the compound is neutralized when mushrooms are cooked above 293°F, which prevents the reaction.

Eating raw or undercooked shiitake mushrooms (Lentinula edodes) can trigger a distinctive whip-like skin rash that appears 24–72 hours after eating in sensitive people. The reaction is linked to lentinan, a mushroom polysaccharide that can trigger a hypersensitivity response and produce linear red lesions across the trunk and arms. The condition is rare with ~150 cases reported worldwide and the compound is neutralized when mushrooms are cooked above 293°F, which prevents the reaction.

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