Gut & Digestion

·

Study

Reishi Polysaccharides Protected Mice From Colitis

Reishi Polysaccharides Protected Mice From Colitis

Reishi

What they found

Reishi polysaccharides reduced colitis disease scores, weight loss and gut inflammation in mice.

Reishi polysaccharides reduced colitis disease scores, weight loss and gut inflammation in mice.

How solid is it?

Animal

Animal

Animal

Animal

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Ganoderma lucidum

Ganoderma lucidum

Compound

polysaccharides

polysaccharides

Published in

International Journal of Medicinal Mushrooms

International Journal of Medicinal Mushrooms

Covered in Shroom Scan

Section

HEALTH & WELLNESS

HEALTH & WELLNESS

As it ran in Shroom Scan

Colitis Inflammation Relief

Colitis Inflammation Relief

Reishi mushroom (Ganoderma lucidum) polysaccharides helped protect the gut from ulcerative colitis damage in mice. The treatment reduced disease activity scores and prevented DSS-induced weight loss, while boosting antioxidant defenses like superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in the blood. Gut inflammation also dropped, with TNF-α and IL-6 levels significantly reduced, and the microbiome shifted toward healthier bacteria such as Muribaculum.

Reishi mushroom (Ganoderma lucidum) polysaccharides helped protect the gut from ulcerative colitis damage in mice. The treatment reduced disease activity scores and prevented DSS-induced weight loss, while boosting antioxidant defenses like superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in the blood. Gut inflammation also dropped, with TNF-α and IL-6 levels significantly reduced, and the microbiome shifted toward healthier bacteria such as Muribaculum.

Lion’s Mane for Joints, Immune Boost, and Plastic-Eating Fungi,

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