Cancer

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Study

Shiitake During Puberty Lowered Breast Tissue Inflammation in Animals

Shiitake During Puberty Lowered Breast Tissue Inflammation in Animals

Shiitake

What they found

Shiitake extract at 2 g/kg/day during puberty reduced mammary tissue inflammation and shifted DNA methylation by about 5–10%.

Shiitake extract at 2 g/kg/day during puberty reduced mammary tissue inflammation and shifted DNA methylation by about 5–10%.

The number

2 g/kg/day

How solid is it?

Animal

Animal

Animal

Animal

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Lentinula edodes

Lentinula edodes

Published in

The Breast Journal

The Breast Journal

Covered in Shroom Scan

Section

HEALTH & WELLNESS

HEALTH & WELLNESS

As it ran in Shroom Scan

Inflammation Reset Window

Inflammation Reset Window

Shiitake mushroom (Lentinula edodes) extract at 2 g/kg/day during puberty reduced inflammation signals in mammary tissue. It also reversed harmful gene changes by adjusting DNA methylation patterns by ~5–10% in pathways linked to cancer and immune response, showing how early intake can help lower long-term inflammation and reshape disease risk at the genetic level.

Shiitake mushroom (Lentinula edodes) extract at 2 g/kg/day during puberty reduced inflammation signals in mammary tissue. It also reversed harmful gene changes by adjusting DNA methylation patterns by ~5–10% in pathways linked to cancer and immune response, showing how early intake can help lower long-term inflammation and reshape disease risk at the genetic level.

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