Brain & Cognition

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Study

Simulations Suggest Psychedelics Could Stir Damaged Brains Toward Awareness

Simulations Suggest Psychedelics Could Stir Damaged Brains Toward Awareness

Psilocybin mushrooms

What they found

Computer brain models of patients with disorders of consciousness suggest psilocybin and LSD could increase brain network complexity.

Computer brain models of patients with disorders of consciousness suggest psilocybin and LSD could increase brain network complexity.

How solid is it?

Early human

Early human

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin, LSD

psilocybin, LSD

Published in

Translational Psychiatry

Translational Psychiatry

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

Coma Brain Reboot

Coma Brain Reboot

Computer simulations suggest psychedelics like psilocybin and LSD could push damaged brains closer to a “critical” activity state linked to consciousness. In whole-brain models of patients with disorders of consciousness, the drugs increased network complexity and signal integration, patterns associated with more responsive and awake brain dynamics.

Computer simulations suggest psychedelics like psilocybin and LSD could push damaged brains closer to a “critical” activity state linked to consciousness. In whole-brain models of patients with disorders of consciousness, the drugs increased network complexity and signal integration, patterns associated with more responsive and awake brain dynamics.

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