Mood & Mental Health

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Study

Single Psilocybin Dose Helped Some Women With Anorexia in Small Trial

Single Psilocybin Dose Helped Some Women With Anorexia in Small Trial

Psilocybin mushrooms

What they found

In a trial of ten women with anorexia given one dose of synthetic psilocybin (COMP360), 40% had a clinically significant symptom reduction and 90% felt more optimistic.

In a trial of ten women with anorexia given one dose of synthetic psilocybin (COMP360), 40% had a clinically significant symptom reduction and 90% felt more optimistic.

The number

40% of the participants saw a clinically significant reduction in eating disorder psychopathology

How solid is it?

Early human

Early human

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin (COMP360)

psilocybin (COMP360)

Sample size

10 women

10 women

Published in

Shroomer

Shroomer

Covered in Shroom Scan

Section

First psilocybin trial for anorexia nervosa shows successful results

First psilocybin trial for anorexia nervosa shows successful results

As it ran in Shroom Scan

Anorexia Nervosa Has the Highest Mortality Rate of Any Psychiatric Disorder

Anorexia Nervosa Has the Highest Mortality Rate of Any Psychiatric Disorder

There are no proven treatments to reverse the main symptoms or approved medications to treat the disorder. In a recent study, ten women with the condition were given a single dose of an investigational drug called COMP360, a pharmaceutical-grade synthetic psilocybin developed by COMPASS Pathways. Of the participants, 40% of the participants saw a clinically significant reduction in eating disorder psychopathology, and 90% felt more optimistic about their life endeavors. — Seraiah Alexander

There are no proven treatments to reverse the main symptoms or approved medications to treat the disorder. In a recent study, ten women with the condition were given a single dose of an investigational drug called COMP360, a pharmaceutical-grade synthetic psilocybin developed by COMPASS Pathways. Of the participants, 40% of the participants saw a clinically significant reduction in eating disorder psychopathology, and 90% felt more optimistic about their life endeavors. — Seraiah Alexander

Psilocybin may be effective treatment for anorexia nervosa

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