Brain & Cognition

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Study

Single Psilocybin Dose Increased Brain Synapse Density

Single Psilocybin Dose Increased Brain Synapse Density

Psilocybin mushrooms

What they found

A single psilocybin dose increased synaptic density in the frontal cortex and hippocampus of healthy participants.

A single psilocybin dose increased synaptic density in the frontal cortex and hippocampus of healthy participants.

How solid is it?

Early human

Early human

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin

psilocybin

Published in

Research Square

Research Square

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

Neuroplasticity Unlocked

Neuroplasticity Unlocked

A single dose of psilocybin increased synaptic density in the frontal cortex and hippocampus of healthy participants who received the treatment in a therapeutic setting. Those with more intense mystical experiences showed stronger neuroplastic changes and longer-lasting positive effects.

A single dose of psilocybin increased synaptic density in the frontal cortex and hippocampus of healthy participants who received the treatment in a therapeutic setting. Those with more intense mystical experiences showed stronger neuroplastic changes and longer-lasting positive effects.

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