Mood & Mental Health

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Study

Single Psilocybin Dose Rapidly Eases Depression and Anxiety in Cancer Patients

Single Psilocybin Dose Rapidly Eases Depression and Anxiety in Cancer Patients

Psilocybin mushrooms

What they found

One 0.3 mg/kg psilocybin dose cut depression and anxiety scores within a day in cancer patients, with anxiety relief lasting at least two weeks.

One 0.3 mg/kg psilocybin dose cut depression and anxiety scores within a day in cancer patients, with anxiety relief lasting at least two weeks.

The number

0.3 mg/kg dose

How solid is it?

Early human

Early human

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin

psilocybin

Published in

The International Journal of Psychiatry in Medicine

The International Journal of Psychiatry in Medicine

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

Cancer Care Relief

Cancer Care Relief

Psilocybin quickly eased depression and anxiety symptoms in cancer patients. A single 0.3 mg/kg dose—about 21 mg for a 154 lb adult—significantly reduced depression and anxiety scores within one day, with anxiety relief lasting at least two weeks. This moderate-to-high dose supports psilocybin’s promise as a rapid-acting therapy in palliative and end-of-life care.

Psilocybin quickly eased depression and anxiety symptoms in cancer patients. A single 0.3 mg/kg dose—about 21 mg for a 154 lb adult—significantly reduced depression and anxiety scores within one day, with anxiety relief lasting at least two weeks. This moderate-to-high dose supports psilocybin’s promise as a rapid-acting therapy in palliative and end-of-life care.

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