Metabolic & Heart

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Study

Split-Gill Polysaccharide Reduced Obesity in Mice via Gut Changes

Split-Gill Polysaccharide Reduced Obesity in Mice via Gut Changes

Split-gill mushroom

What they found

A split-gill mushroom polysaccharide reduced obesity in mice by boosting a beneficial gut microbe and indole-3-lactic acid.

A split-gill mushroom polysaccharide reduced obesity in mice by boosting a beneficial gut microbe and indole-3-lactic acid.

How solid is it?

Animal

Animal

Animal

Animal

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Schizophyllum commune

Schizophyllum commune

Compound

polysaccharide; indole-3-lactic acid

polysaccharide; indole-3-lactic acid

Published in

Carbohydrate Polymers

Carbohydrate Polymers

Covered in Shroom Scan

Section

HEALTH & WELLNESS

HEALTH & WELLNESS

As it ran in Shroom Scan

Metabolism Booster

Metabolism Booster

A polysaccharide from the split-gill mushroom (Schizophyllum commune) helped reduce obesity in mice by reshaping key gut pathways. It increased levels of the beneficial microbe Faecalibaculum rodentium and boosted indole-3-lactic acid, a gut-derived metabolite linked to healthier inflammation and metabolism. These changes also shifted microRNA activity tied to fat regulation.

A polysaccharide from the split-gill mushroom (Schizophyllum commune) helped reduce obesity in mice by reshaping key gut pathways. It increased levels of the beneficial microbe Faecalibaculum rodentium and boosted indole-3-lactic acid, a gut-derived metabolite linked to healthier inflammation and metabolism. These changes also shifted microRNA activity tied to fat regulation.

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