Mood & Mental Health

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Study

Weekly Psilocybin Reverses Depression-Like Signs in Stressed Mice

Weekly Psilocybin Reverses Depression-Like Signs in Stressed Mice

Psilocybin mushrooms

What they found

A weekly psilocybin dose reversed depression-like symptoms and restored serotonin and BDNF in chronically stressed mice.

A weekly psilocybin dose reversed depression-like symptoms and restored serotonin and BDNF in chronically stressed mice.

How solid is it?

Animal

Animal

Animal

Animal

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Compound

psilocybin

psilocybin

Published in

Translational Psychiatry

Translational Psychiatry

Covered in Shroom Scan

Section

PSILOCYBIN & LEGISLATION

PSILOCYBIN & LEGISLATION

As it ran in Shroom Scan

Chronic Stress Relief

Chronic Stress Relief

Psilocybin significantly reversed depression-like symptoms in mice exposed to chronic stress. A single weekly dose improved motivation, reduced anxiety, and restored brain chemicals like serotonin and BDNF.

Psilocybin significantly reversed depression-like symptoms in mice exposed to chronic stress. A single weekly dose improved motivation, reduced anxiety, and restored brain chemicals like serotonin and BDNF.

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