Immunity & Infection

·

Study

Wine Cap Polysaccharides Helped Mice Recover Immunity After Chemo

Wine Cap Polysaccharides Helped Mice Recover Immunity After Chemo

Wine cap

What they found

Wine cap polysaccharides restored immune balance and protected the liver in mice after cyclophosphamide chemotherapy.

Wine cap polysaccharides restored immune balance and protected the liver in mice after cyclophosphamide chemotherapy.

How solid is it?

Animal

Animal

Animal

Animal

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Stropharia rugosoannulata

Stropharia rugosoannulata

Compound

polysaccharides

polysaccharides

Published in

Journal of the Science of Food and Agriculture

Journal of the Science of Food and Agriculture

Covered in Shroom Scan

Section

HEALTH & WELLNESS

HEALTH & WELLNESS

As it ran in Shroom Scan

Immune Rebound

Immune Rebound

Wine cap mushroom (Stropharia rugosoannulata) polysaccharides helped mice regain immune strength after cyclophosphamide, a chemotherapy drug known to suppress immunity and strain the liver. The extract restored white blood cell balance, increased key immune signals (like IgA and IgG), and activated the TLR4 pathway that controls immune defense. It also protected liver tissue by lowering damage markers (ALT and AST) and improving antioxidant activity, helping the body recover more smoothly from treatment.

Wine cap mushroom (Stropharia rugosoannulata) polysaccharides helped mice regain immune strength after cyclophosphamide, a chemotherapy drug known to suppress immunity and strain the liver. The extract restored white blood cell balance, increased key immune signals (like IgA and IgG), and activated the TLR4 pathway that controls immune defense. It also protected liver tissue by lowering damage markers (ALT and AST) and improving antioxidant activity, helping the body recover more smoothly from treatment.

Shiitake for Skin Defense, Wine Cap for Recovery, and Psilocybin’s Nuance

Read the original study ↗

Get Shroom Scan

Next study

Fermented Shiitake Broth Protected Mouse Livers From Alcohol ›

Shroom Scan · Every Friday

Get Studies Like This, Translated, Every Week

Ten new studies a week, each boiled down to what it found and why it matters to you. Free, and one click to leave.

See what's inside →