Cancer

·

Study

Artist's Conk Compounds Modeled Against Liver Cancer Targets

Artist's Conk Compounds Modeled Against Liver Cancer Targets

Artist's conk

What they found

In a computer-modeling study, four artist's conk triterpenoids bound strongly to liver cancer-related proteins.

In a computer-modeling study, four artist's conk triterpenoids bound strongly to liver cancer-related proteins.

How solid is it?

Lab dish

Lab dish

Lab – computer modeling

Lab – computer modeling

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Ganoderma applanatum

Ganoderma applanatum

Compound

triterpenoids

triterpenoids

Published in

International Journal of Medicinal Mushrooms

International Journal of Medicinal Mushrooms

Covered in Shroom Scan

Section

HEALTH & WELLNESS

HEALTH & WELLNESS

As it ran in Shroom Scan

Liver Cancer Fighter

Liver Cancer Fighter

Compounds from the artist’s conk mushroom (Ganoderma applanatum) showed multi-pathway potential against liver cancer in a computer-modeling study. Four triterpenoids strongly bound to major cancer-related proteins such as AKT1, MAPK1, and SRC, which help drive tumor growth. Some compounds also showed low predicted toxicity.

Compounds from the artist’s conk mushroom (Ganoderma applanatum) showed multi-pathway potential against liver cancer in a computer-modeling study. Four triterpenoids strongly bound to major cancer-related proteins such as AKT1, MAPK1, and SRC, which help drive tumor growth. Some compounds also showed low predicted toxicity.

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