Brain & Cognition

·

Study

Chaga Compound Improves Memory and Calms Brain Inflammation in Mice

Chaga Compound Improves Memory and Calms Brain Inflammation in Mice

Chaga

What they found

One of eight chaga triterpenoids lowered inflammation in cells and improved learning in memory-impaired mice.

One of eight chaga triterpenoids lowered inflammation in cells and improved learning in memory-impaired mice.

The number

eight lanostane-type triterpenoids

How solid is it?

Animal

Animal

Animal

Animal

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Inonotus obliquus

Inonotus obliquus

Compound

lanostane-type triterpenoids

lanostane-type triterpenoids

Published in

Fitoterapia

Fitoterapia

Covered in Shroom Scan

Section

HEALTH & WELLNESS

HEALTH & WELLNESS

As it ran in Shroom Scan

Jumpstart Memory

Jumpstart Memory

Chaga mushrooms (Inonotus obliquus) contain eight lanostane-type triterpenoids, with one compound showing the strongest brain benefits. In cell models, it cut inflammation by lowering nitric oxide and dialing down pro-inflammatory signals like COX-2, iNOS, IL-1β, IL-6, and TNF-α. In memory-impaired mice, the same compound improved learning and suppressed harmful inflammation while protecting growth factors NGF and BDNF, which are crucial for brain health.

Chaga mushrooms (Inonotus obliquus) contain eight lanostane-type triterpenoids, with one compound showing the strongest brain benefits. In cell models, it cut inflammation by lowering nitric oxide and dialing down pro-inflammatory signals like COX-2, iNOS, IL-1β, IL-6, and TNF-α. In memory-impaired mice, the same compound improved learning and suppressed harmful inflammation while protecting growth factors NGF and BDNF, which are crucial for brain health.

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