Skin & Aging

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Study

Golden Oyster Ergothioneine Reduced Wrinkles in 28-Day Trial

Golden Oyster Ergothioneine Reduced Wrinkles in 28-Day Trial

Golden oyster

What they found

Taking 100 mg ergothioneine from golden oyster mushrooms daily for 28 days cut wrinkles by 21% and improved skin hydration and elasticity.

Taking 100 mg ergothioneine from golden oyster mushrooms daily for 28 days cut wrinkles by 21% and improved skin hydration and elasticity.

The number

fewer wrinkles (–21%)

How solid is it?

Early human

Early human

Evidence ladder: Lab dish → Animal → Early human → Strong human. Reviews summarize earlier research.

At a glance

Latin name

Pleurotus citrinopileatus

Pleurotus citrinopileatus

Compound

ergothioneine

ergothioneine

Published in

Francis Academic Press

Francis Academic Press

Covered in Shroom Scan

Section

HEALTH & WELLNESS

HEALTH & WELLNESS

As it ran in Shroom Scan

Skin Aging Slowdown

Skin Aging Slowdown

Ergothioneine, a natural antioxidant extracted from golden oyster mushrooms (Pleurotus citrinopileatus), showed strong anti-aging benefits in a 28-day clinical trial. Participants taking 100 mg daily had brighter skin (+3.6% gloss), better elasticity (+5.4%), improved hydration (+7.6%), and fewer wrinkles (–21%). The compound also blocked harmful glycation, one of the key processes behind collagen damage, supporting its use in skincare and wellness applications.

Ergothioneine, a natural antioxidant extracted from golden oyster mushrooms (Pleurotus citrinopileatus), showed strong anti-aging benefits in a 28-day clinical trial. Participants taking 100 mg daily had brighter skin (+3.6% gloss), better elasticity (+5.4%), improved hydration (+7.6%), and fewer wrinkles (–21%). The compound also blocked harmful glycation, one of the key processes behind collagen damage, supporting its use in skincare and wellness applications.

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